Description

(Ala6,D-Trp8,L-Alaninol15)-Galanin (1-15) CAS NO 184683-37-2 is a synthetic, modified peptide analog of the neuropeptide Galanin, designed for enhanced stability and receptor interaction. This compound is a critical research tool for investigating the role of galaninergic systems in physiological and pathological processes. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies focused on neuroscience, metabolic disorders, and pain management research.

Application

• Neuroscience Research: Used as a potent and selective ligand for studying galanin receptor (GalR) subtypes (GalR1, GalR2, GalR3) in the central and peripheral nervous systems.
• Pharmacological Studies: Serves as a reference standard and active agent in assays to evaluate receptor binding affinity, signal transduction, and functional activity.
• Drug Discovery: A key intermediate or lead compound in the development of novel therapeutics targeting pain, epilepsy, Alzheimer's disease, and mood disorders.
• Metabolic Research: Investigated for its effects on insulin secretion, feeding behavior, and energy homeostasis due to galanin's role in metabolism.
• Biochemical Tool: Employed in structure-activity relationship (SAR) studies to understand the impact of specific amino acid substitutions (Ala6, D-Trp8, L-Alaninol15) on peptide stability and potency.

Basic Information

Product Name	(Ala6,D-Trp8,L-Alaninol15)-Galanin (1-15)
CAS No.	184683-37-2
Molecular Formula	C81H118N22O19
Molecular Weight	1664.0 g/mol (approx.)
Synonyms	Galanin (1-15) amide, [Ala6, D-Trp8, L-Alaninol15]-; [Ala6,D-Trp8,L-Alaninol15]Galanin(1-15); Galanin(1-15) analog; Modified Galanin fragment; Galanin receptor ligand; Galanin amide (1-15) analog; Neuropeptide Galanin analog
EINECS	Contact for details

Quality Control

Every batch of (Ala6,D-Trp8,L-Alaninol15)-Galanin (1-15) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality commitment aligns with standards expected for research-grade bioactive peptides. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for purity (HPLC), molecular weight (MS), and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Molecular Weight (MS)	1664.0 ± 2.0 Da
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/IC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.