Description

L-Glutamine-13C5 is a stable isotope-labeled analog of the essential amino acid L-glutamine, where all five carbon atoms are replaced with the carbon-13 isotope. This high-purity labeled compound is critical for advanced research requiring precise metabolic tracing and quantification. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic developers in the fields of metabolomics, stable isotope-resolved metabolomics (SIRM), and drug development studies.

Application

• Metabolic Pathway Tracing: Used as an internal standard and tracer in mass spectrometry (MS) and nuclear magnetic resonance (NMR) studies to elucidate glutamine metabolism in cancer cells, immune cells, and other biological systems.
• Quantitative Proteomics & Metabolomics: Serves as a crucial standard for the accurate absolute quantification of glutamine and its metabolites in complex biological samples.
• Drug Metabolism and Pharmacokinetics (DMPK): Employed in the development and validation of bioanalytical methods for tracking the fate of new drug candidates.
• Nutritional Research: Applied in clinical and preclinical studies to investigate glutamine utilization, turnover, and its role in conditions like muscle wasting, gut health, and immune function.
• Diagnostic Assay Development: Used as a calibrant and reference material in the development of in vitro diagnostic (IVD) tests and clinical assays.

Basic Information

Product Name	L-Glutamine-13C5
CAS No.	184161-19-1
Molecular Formula	¹³C₅H₁₀N₂O₃
Molecular Weight	151.10 g/mol (for ¹³C₅)
Synonyms	(2S)-2-Amino-4-carbamoyl-¹³C₅-butyric acid; L-Glutamine-¹³C₅; Glutamine-13C5; (S)-2,5-Diamino-5-oxo-¹³C₅-pentanoic acid; GLN-13C5; 13C5-L-Glutamine; 13C Labeled L-Glutamine; Stable Isotope Labeled L-Glutamine
EINECS	Contact for details

Quality Control

Our L-Glutamine-13C5 is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity, essential for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically ≥99 atom % ¹³C), chemical purity (by HPLC), chiral purity, and other critical parameters. We adhere to cGMP principles for research-grade materials, ensuring traceability, consistency, and reliability for your long-term studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥99 atom % ¹³C
Specific Rotation	+31.5° to +34.0° (c=2, in H₂O)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.