Description

(D-Bpa13,Tyr19)-Mch (Human, Mouse, Rat) CAS NO 183606-10-2 is a synthetic, site-specifically modified melanin-concentrating hormone (MCH) peptide analog designed for advanced research applications. This compound matters for its role as a critical biochemical tool in studying the MCH receptor system, a key target in metabolic and neurological research. It is primarily needed by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on obesity, energy homeostasis, and central nervous system disorders.

Application

• Biochemical Research: Used as a high-affinity ligand in receptor binding assays and functional studies for MCH receptors (MCHR1 and MCHR2).
• Drug Discovery & Development: Serves as a reference standard and pharmacological probe in screening programs for novel anti-obesity and antidepressant therapeutics.
• Metabolic Pathway Analysis: Facilitates the study of MCH's role in appetite regulation, energy balance, and glucose metabolism in human, mouse, and rat models.
• Neuroscience Investigations: Employed in research exploring the neuromodulatory functions of MCH in sleep, stress, reward, and mood-related behaviors.
• In Vitro & In Vivo Studies: Applicable in cell-based assays (e.g., cAMP accumulation, calcium mobilization) and animal model studies to validate target engagement.
• Proteomics & Signal Transduction: A tool for investigating downstream signaling pathways and protein interactions mediated by MCH receptor activation.

Basic Information

Product Name	(D-Bpa13,Tyr19)-Mch (Human, Mouse, Rat)
CAS No.	183606-10-2
Molecular Formula	C148H238N42O43S
Molecular Weight	3297.8 g/mol
Synonyms	[D-Bpa13,Tyr19]-Melanin Concentrating Hormone; (D-Bpa13,Tyr19)-Melanin-Concentrating Hormone (human, mouse, rat); (D-Bpa13,Tyr19)-MCH; MCH (13-D-Bpa, 19-Tyr); 4-Benzoyl-D-phenylalanine13, Tyrosine19-MCH; Modified Melanin-Concentrating Hormone Peptide; MCH Receptor Probe; MCH Analog
EINECS	Contact for details

Quality Control

Our (D-Bpa13,Tyr19)-Mch is produced under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC-MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.