Description

5-Bromo-4-Chloro-2-(Methylthio)-7H-Pyrrolo[2,3-D]Pyrimidine is a high-purity, heterocyclic organic building block of significant importance in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate for the creation of novel kinase inhibitors and other targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of new drugs for oncology and inflammatory diseases.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of protein kinase inhibitors for targeted cancer therapies.
• Biochemical Research: Used as a scaffold molecule in structure-activity relationship (SAR) studies and high-throughput screening.
• Agrochemical Development: Serves as a building block for creating novel active ingredients with potential fungicidal or herbicidal properties.
• Organic Synthesis: Valuable reagent for constructing complex pyrrolopyrimidine-based libraries for medicinal chemistry.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	5-Bromo-4-Chloro-2-(Methylthio)-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	183274-54-6
Molecular Formula	C7H5BrClN3S
Molecular Weight	294.56 g/mol
Synonyms	5-Bromo-4-chloro-2-(methylthio)-7H-pyrrolo[2,3-d]pyrimidine; 2-(Methylthio)-5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-5-bromo-2-methylsulfanyl-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 5-bromo-4-chloro-2-(methylthio)-; BCPMP; 5-Bromo-4-chloro-2-methylmercapto-7H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Chloro-2-(Methylthio)-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.