Description

N~1~,N~1~-Dimethyl-4-(Trifluoromethyl)-1,2-Benzenediamine (Saltdata: Free) is a high-purity, functionalized aromatic diamine building block characterized by its dimethylamino and trifluoromethyl substituents. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique electronic and steric properties are leveraged. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas where the trifluoromethyl group enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the structural motif contributes to product efficacy and environmental persistence profiles.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Polymer and Material Science: Employed in the production of high-performance polymers, such as polyimides or epoxy resins, where it can impart unique thermal and chemical resistance properties.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing specialized dyes and organic pigments, utilizing the amine groups for chromophore development.
• Organic Synthesis Building Block: A versatile reagent for introducing the dimethylamino and trifluoromethylphenyl groups into more complex molecules via further functionalization reactions like coupling or cyclization.

Basic Information

Product Name	N~1~,N~1~-Dimethyl-4-(Trifluoromethyl)-1,2-Benzenediamine (Saltdata: Free)
CAS No.	183251-95-8
Molecular Formula	C9H11F3N2
Molecular Weight	204.19 g/mol
Synonyms	4-(Trifluoromethyl)-N~1~,N~1~-dimethylbenzene-1,2-diamine; 1,2-Benzenediamine, N~1~,N~1~-dimethyl-4-(trifluoromethyl)-; 2-Amino-N,N-dimethyl-4-(trifluoromethyl)aniline; N,N-Dimethyl-4-(trifluoromethyl)-1,2-phenylenediamine; 4-(Trifluoromethyl)-o-phenylenediamine N,N-dimethyl derivative; 2-Amino-α,α,α-trifluoro-p-toluidine, N,N-dimethyl-; 183251-95-8 (CAS Name)
EINECS	Contact for details

Quality Control

Our N~1~,N~1~-Dimethyl-4-(Trifluoromethyl)-1,2-Benzenediamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.