Description

2-(2-Fluorophenoxy)-5-(Trifluoromethyl)Aniline is a high-purity fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which combines a fluorophenoxy group with a trifluoromethyl-substituted aniline, enabling precise modifications to target properties in final compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing advanced colorants with improved lightfastness and chemical resistance.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) to construct complex nitrogen-containing heterocycles.

Basic Information

Product Name	2-(2-Fluorophenoxy)-5-(Trifluoromethyl)Aniline
CAS No.	183111-15-1
Molecular Formula	C13H9F4NO
Molecular Weight	271.21 g/mol
Synonyms	5-(Trifluoromethyl)-2-(2-fluorophenoxy)aniline; 2-(2-Fluorophenoxy)-5-(trifluoromethyl)benzenamine; 2-Amino-4'-(trifluoromethyl)-2'-fluorodiphenyl ether; 2-(2-Fluorophenoxy)-α,α,α-trifluoro-p-toluidine; Benzenamine, 2-(2-fluorophenoxy)-5-(trifluoromethyl)-; 183111-15-1; 2-(2-Fluorophenoxy)-5-trifluoromethylaniline
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Fluorophenoxy)-5-(Trifluoromethyl)Aniline is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.