Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-8-Ethoxy-6-Fluoro-1,4-Dihydro-7-[3-[(Methylamino)Methyl]-1-Pyrrolidinyl]-4-Oxo- is a high-purity advanced pharmaceutical intermediate of significant commercial importance. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly within the fluoroquinolone antibiotic class. It is essential for R&D laboratories and manufacturing facilities focused on developing and producing next-generation antibacterial agents.

Application

• Key Intermediate for Fluoroquinolone Antibiotics: Serves as a crucial building block in the synthesis of potent antibacterial agents.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the discovery and optimization of novel antibacterial compounds.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the commercial-scale production of finished drug substances.
• Process Chemistry & Scale-Up: Integral for developing efficient and scalable synthetic routes in pilot plants and production facilities.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-8-Ethoxy-6-Fluoro-1,4-Dihydro-7-[3-[(Methylamino)Methyl]-1-Pyrrolidinyl]-4-Oxo-
CAS No.	182868-80-0
Molecular Formula	C21H26FN3O4
Molecular Weight	403.45 g/mol
Synonyms	1-Cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-[3-[(methylamino)methyl]-1-pyrrolidinyl]-4-oxo-3-quinolinecarboxylic acid; Garenoxacin Intermediate; Garenoxacin Quinoline Core; AM-1155 Intermediate; BMS-284756 Intermediate; T-3811 Intermediate; 7-(3-[(Methylamino)methyl]pyrrolidin-1-yl)-1-cyclopropyl-8-ethoxy-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. Production can be aligned with cGMP standards upon request for advanced pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.