Description

3-Quinolinecarboxylic Acid, 7-(3-Amino-1-Pyrrolidinyl)-1-Cyclopropyl-8-Ethoxy-6-Fluoro-1,4-Dihydro-4-Oxo- is a high-purity advanced pharmaceutical intermediate (API intermediate) of significant commercial and research interest. Its complex molecular structure, featuring a quinoline core with a pyrrolidinyl substituent, makes it a critical building block in the synthesis of novel fluoroquinolone antibiotics. This compound is essential for pharmaceutical R&D and manufacturing entities focused on developing next-generation antibacterial agents. Suppliers must provide consistent quality and reliable documentation to support stringent regulatory requirements.

Application

• Pharmaceutical Intermediate: Primary use as a key building block in the synthesis of advanced fluoroquinolone antibiotic candidates.
• Antibacterial Drug Research: Serves as a core scaffold in medicinal chemistry for developing new antibacterial agents with improved efficacy and spectrum.
• Process Chemistry & Scale-Up: Used in process development and optimization studies for commercial API manufacturing routes.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Chemical Synthesis: Utilized in organic synthesis for constructing complex heterocyclic systems with potential biological activity.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations specializing in the production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 7-(3-Amino-1-Pyrrolidinyl)-1-Cyclopropyl-8-Ethoxy-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	182868-77-5
Molecular Formula	C19H22FN3O4
Molecular Weight	375.40 g/mol
Synonyms	7-(3-Aminopyrrolidin-1-yl)-1-cyclopropyl-8-ethoxy-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-8-ethoxy-6-fluoro-7-(3-aminopyrrolidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid; Garenoxacin Intermediate; Garenoxacin Impurity; Garenoxacin Related Compound; AM-1155 Intermediate; T-3811 Intermediate; 1,4-Dihydro-4-oxo-7-(3-aminopyrrolidin-1-yl)-1-cyclopropyl-8-ethoxy-6-fluoro-3-quinolinecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid, 7-(3-Amino-1-Pyrrolidinyl)-1-Cyclopropyl-8-Ethoxy-6-Fluoro-1,4-Dihydro-4-Oxo- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards suitable for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.