Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-8-Ethoxy-6-Fluoro-1,4-Dihydro-7-(3-Methyl-1-Piperazinyl)-4-Oxo- is a high-purity, complex fluoroquinolone derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmaceutical intermediate or reference standard in the synthesis of novel antibacterial agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing next-generation antibiotic therapies. Our supply ensures the stringent quality and consistency necessary for sensitive synthetic pathways and analytical applications.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new fluoroquinolone-class antibiotic compounds.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) of antibacterial agents.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the development and scale-up processes for novel API candidates.
• Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Item	Details
Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-8-Ethoxy-6-Fluoro-1,4-Dihydro-7-(3-Methyl-1-Piperazinyl)-4-Oxo-
CAS No.	182868-72-0
Molecular Formula	C20H24FN3O4
Molecular Weight	389.42 g/mol
Synonyms	1-Cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid; 8-Ethoxy-6-fluoro-1-cyclopropyl-1,4-dihydro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid; Garenoxacin Intermediate; Garenoxacin Carboxylic Acid Derivative; BMS-284756 Intermediate; T-3811 Intermediate; 3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-8-ethoxy-6-fluoro-7-(3-methyl-1-piperazinyl)-4-oxo-; 4-Oxo-1-cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-(3-methylpiperazin-1-yl)quinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is produced under controlled conditions to meet the exacting standards of pharmaceutical research. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure consistency and reliability. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.