Description

4-(2-Pyrimidinyl)-1-Piperidinecarboxylic Acid 1,1-Dimethylethyl Ester is a high-purity, protected piperidine derivative that serves as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its value lies in enabling the efficient construction of complex molecules, particularly for research and development in medicinal chemistry. This compound is essential for pharmaceutical manufacturers and contract research organizations (CROs) focused on developing new active pharmaceutical ingredients (APIs), especially in therapeutic areas targeting the central nervous system and oncology.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in the design and development of new chemical entities, particularly for structure-activity relationship (SAR) studies.
• Ligand and Scaffold Synthesis: Serves as a precursor for creating complex heterocyclic scaffolds and ligands for biological targets.
• Process Chemistry Development: Employed in route scouting and optimization for scalable manufacturing processes.
• Academic and Industrial R&D: Utilized in laboratories for exploratory synthesis and method development.
• Agrochemical Intermediate: Potential use in the synthesis of advanced crop protection agents.

Basic Information

Item	Detail
Product Name	4-(2-Pyrimidinyl)-1-Piperidinecarboxylic Acid 1,1-Dimethylethyl Ester
CAS No.	182416-05-3
Molecular Formula	C14H21N3O2
Molecular Weight	263.34 g/mol
Synonyms	tert-Butyl 4-(pyrimidin-2-yl)piperidine-1-carboxylate; 1-Boc-4-(2-pyrimidinyl)piperidine; 1-(tert-Butoxycarbonyl)-4-(2-pyrimidinyl)piperidine; 4-(Pyrimidin-2-yl)piperidine-1-carboxylic acid tert-butyl ester; Boc-4-(2-pyrimidyl)piperidine; N-Boc-4-(2-pyrimidinyl)piperidine; 4-(2-Pyrimidinyl)-1-piperidinecarboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 4-(2-Pyrimidinyl)-1-Piperidinecarboxylic Acid 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports compliance with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.