Description

(R)-1-Pyrimidin-2-Yl-Pyrrolidin-3-Ol is a high-purity chiral building block and intermediate of significant importance in modern synthetic chemistry. This compound matters because its defined stereochemistry and heterocyclic structure make it a valuable scaffold for constructing complex, biologically active molecules. Pharmaceutical and agrochemical research organizations need it for the development of novel active ingredients, particularly in areas requiring precise molecular recognition.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and antiviral targets.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers with unique properties.

Basic Information

Product Name	(R)-1-Pyrimidin-2-Yl-Pyrrolidin-3-Ol
CAS No.	181959-76-2
Molecular Formula	C8H11N3O
Molecular Weight	165.19 g/mol
Synonyms	(3R)-1-(Pyrimidin-2-yl)pyrrolidin-3-ol; (R)-3-Hydroxy-1-(pyrimidin-2-yl)pyrrolidine; (R)-1-(2-Pyrimidinyl)-3-pyrrolidinol; Pyrrolidin-3-ol, 1-(2-pyrimidinyl)-, (3R)-; 181959-76-2; (R)-1-(Pyrimidin-2-yl)pyrrolidin-3-ol; (R)-N-(Pyrimidin-2-yl)-3-hydroxypyrrolidine
EINECS	Contact for details

Quality Control

Our (R)-1-Pyrimidin-2-Yl-Pyrrolidin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.