Description

6-Amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-5-pyrimidinecarbothioaldehyde is a high-purity, advanced pharmaceutical intermediate with the CAS number 181465-38-3. This compound is a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of nucleoside analogs and other therapeutic agents. It is essential for research and manufacturing organizations in the pharmaceutical, biotechnology, and fine chemical sectors seeking to develop innovative drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside and pyrimidine-based active pharmaceutical ingredients (APIs).
• Antiviral Drug Research: Used in the R&D of potential antiviral and anticancer agents targeting nucleic acid synthesis.
• Biochemical Research: Serves as a specialized reagent for studying enzyme inhibition and metabolic pathways.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for complex, high-value organic molecules.
• Agrochemical Development: Potential intermediate in the research of new crop protection agents and pesticides.

Basic Information

Product Name	6-Amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-5-pyrimidinecarbothioaldehyde
CAS No.	181465-38-3
Molecular Formula	C7H9N3O2S
Molecular Weight	199.23 g/mol
Synonyms	5-Formyl-6-amino-1,3-dimethyluracil-2-thione; 6-Amino-1,3-dimethyl-5-formyl-2-thiouracil; 6-Amino-1,3-dimethyl-2-thio-5-pyrimidinecarboxaldehyde; 6-Amino-1,3-dimethyl-2-thioxo-2,3-dihydro-1H-pyrimidine-5-carbaldehyde; 5-Pyrimidinecarbothioaldehyde, 6-amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-; 1,3-Dimethyl-6-amino-2-thiouracil-5-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 6-Amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-5-pyrimidinecarbothioaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent oxidation and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.