Description

2,4-Dichloro-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other targeted therapies. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key scaffold for the synthesis of potential kinase inhibitors targeting various disease pathways.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Chemical Biology Probes: Serves as a core structure for developing tool compounds to study biological mechanisms.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value organic molecules.
• Agrochemical Research: Potential intermediate for developing new active ingredients with novel modes of action.

Basic Information

Product Name	2,4-Dichloro-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine
CAS No.	181374-43-6
Molecular Formula	C7H6Cl2N2S
Molecular Weight	221.11 g/mol
Synonyms	2,4-Dichloro-5H,7H,8H-thiopyrano[4,3-d]pyrimidine; 2,4-Dichloro-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine; Thiopyrano[4,3-d]pyrimidine, 2,4-dichloro-7,8-dihydro-5H-; 181374-43-6; 2,4-Dichloro-5H-thiopyrano[4,3-d]pyrimidine; 2,4-Dichloro-7,8-dihydro-5H-thieno[3,2-d]pyrimidine (related structural name); 5H-Thiopyrano[4,3-d]pyrimidine, 2,4-dichloro-7,8-dihydro-
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.