Description

4-Pyrimidinemethanamine, 2-Chloro- (9Ci) is a versatile halogenated pyrimidine derivative, a key heterocyclic building block in advanced organic synthesis. Its primary value lies in serving as a crucial intermediate for the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce functionalized pyrimidine scaffolds into complex molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Serves as a building block for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and photoactive compounds.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up production in fine chemical manufacturing.
• Academic & R&D: Used in university and corporate research laboratories for exploring new chemical reactions and biological activities.

Basic Information

Product Name	4-Pyrimidinemethanamine, 2-Chloro- (9Ci)
CAS No.	181363-10-0
Molecular Formula	C5H6ClN3
Molecular Weight	143.57 g/mol
Synonyms	2-Chloro-4-pyrimidinemethanamine; (2-Chloropyrimidin-4-yl)methanamine; 2-Chloro-4-(aminomethyl)pyrimidine; 4-(Aminomethyl)-2-chloropyrimidine; 2-Chloro-4-pyrimidinylmethylamine; 181363-10-0; 2-Chloro-4-(aminomethyl)pyrimidine hydrochloride (if applicable)
EINECS	Contact for details

Quality Control

Our 4-Pyrimidinemethanamine, 2-Chloro- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical and fine chemical industries, supporting your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.