Description

n-(4-Nitrophenyl)-4-(3-Pyridyl)-2-Pyrimidineamine is a high-purity organic compound with the CAS number 181065-58-7, serving as a crucial advanced intermediate in pharmaceutical research and development. Its complex heterocyclic structure makes it a valuable building block for synthesizing novel active pharmaceutical ingredients (APIs) and bioactive molecules. This compound is primarily targeted at R&D laboratories and pharmaceutical manufacturers engaged in the discovery of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in oncology and kinase inhibitor research.
• Biochemical Research: Used as a reference standard or a precursor in studies involving enzyme inhibition and cellular signaling pathways.
• Agrochemical Development: Potential intermediate for creating new crop protection agents and pesticides due to its pyrimidine core.
• Material Science Research: Investigated as a precursor for organic electronic materials and metal-organic frameworks (MOFs).
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for exploratory chemistry and method development.

Basic Information

Product Name	n-(4-Nitrophenyl)-4-(3-Pyridyl)-2-Pyrimidineamine
CAS No.	181065-58-7
Molecular Formula	C15H11N5O2
Molecular Weight	293.28 g/mol
Synonyms	4-(3-Pyridinyl)-N-(4-nitrophenyl)-2-pyrimidinamine; 4-(Pyridin-3-yl)-N-(4-nitrophenyl)pyrimidin-2-amine; 181065-58-7; 4-(3-Pyridyl)-N-(4-nitrophenyl)-2-pyrimidinamine; 2-Pyrimidinamine, 4-(3-pyridinyl)-N-(4-nitrophenyl)-; N-(4-Nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our n-(4-Nitrophenyl)-4-(3-Pyridyl)-2-Pyrimidineamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.