Description

Leucine, n-(n-Acetylglycyl)- (9Ci) is a specialized peptide derivative, specifically an N-acetylated dipeptide of glycine and leucine. This compound is of significant interest in advanced biochemical research and pharmaceutical development due to its role as a building block and model substrate. It serves as a critical intermediate for researchers and manufacturers in the fields of peptide synthesis, proteomics, and medicinal chemistry. Its defined structure makes it valuable for studying enzyme kinetics, metabolic pathways, and for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Used in the research and synthesis of more complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Serves as a standard or substrate in enzymatic studies, particularly those involving peptidases or metabolic enzymes related to leucine and glycine.
• Proteomics & Peptide Chemistry: Acts as a building block in solid-phase and solution-phase peptide synthesis for creating custom peptide sequences.
• Reference Standard: Employed as a high-purity analytical standard in HPLC, LC-MS, or NMR for method development and quality control in laboratories.
• Nutritional Science Research: Investigated for its potential role in metabolic studies, given its derivation from the essential amino acid leucine.

Basic Information

Product Name	Leucine, n-(n-Acetylglycyl)- (9Ci)
CAS No.	180923-15-3
Molecular Formula	C10H18N2O4
Molecular Weight	230.26 g/mol
Synonyms	N-Acetylglycyl-L-leucine; N-Ac-Gly-Leu-OH; Ac-Gly-Leu; L-Leucine, N-acetyl-N-glycyl-; Nα-Acetylglycyl-L-leucine; Glycine, N-acetyl-, L-leucine salt; Acetyl-glycyl-leucine; (2S)-2-[(2-Acetamidoacetamido)]-4-methylpentanoic acid
EINECS	Contact for details

Quality Control

Our Leucine, n-(n-Acetylglycyl)- (9Ci) is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay, chiral purity, and related substances is provided with every shipment. We support compliance with cGMP and research-grade standards for reliable and reproducible results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.