Description

(S)-2-((S)-2-Amino-3-(1H-Imidazol-5-Yl)Propanamido)-5-Guanidinopentanoic Acid Hydrochloride is a high-purity, non-natural amino acid derivative of significant interest in advanced pharmaceutical research and development. This compound, supplied with CAS NO 180894-20-6, is valued for its role as a sophisticated building block in the synthesis of complex peptides and peptidomimetics. It is primarily utilized by research institutions and pharmaceutical companies focused on drug discovery, particularly in areas involving enzyme inhibitors and receptor modulators.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel therapeutic peptides and peptidomimetic drugs.
• Biochemical Research: Used in enzymatic studies and as a substrate or inhibitor analog in protease and kinase research.
• Medicinal Chemistry: Serves as a key scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Proteomics & Peptide Synthesis: Employed in solid-phase and solution-phase peptide synthesis to incorporate specific functional groups (imidazole and guanidine).
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(S)-2-((S)-2-Amino-3-(1H-Imidazol-5-Yl)Propanamido)-5-Guanidinopentanoic Acid Hydrochloride
CAS No.	180894-20-6
Molecular Formula	C12H22ClN7O3
Molecular Weight	347.80 g/mol
Synonyms	L-Arginyl-L-histidine hydrochloride; Arg-His dipeptide hydrochloride; H-Arg-His-OH · HCl; (S)-2-((S)-2-Amino-3-(1H-imidazol-4-yl)propanamido)-5-guanidinopentanoic acid hydrochloride; 180894-20-6; UNII-9K5N8P3B4P; Arginine histidine salt hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-2-((S)-2-Amino-3-(1H-Imidazol-5-Yl)Propanamido)-5-Guanidinopentanoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.