Description

1-(3,5-Difluorophenyl)Piperazine is a high-purity, fluorinated piperazine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the difluorophenylpiperazine moiety, a key pharmacophore in medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially in neuroscience and psychiatry.
• Medicinal Chemistry Research: Used as a core scaffold or building block for constructing compound libraries targeting serotonin and dopamine receptors.
• API Synthesis: Employed in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs) requiring the 3,5-difluorophenylpiperazine structure.
• Biochemical Tool Compound: Serves as a reference standard or starting material for producing ligands used in biochemical assays and pharmacological studies.
• Fine Chemical Production: Integrated into custom synthesis projects for producing specialized fluorinated organic compounds.

Basic Information

Product Name	1-(3,5-Difluorophenyl)Piperazine
CAS No.	180698-14-0
Molecular Formula	C10H12F2N2
Molecular Weight	198.21 g/mol
Synonyms	1-(3,5-Difluorophenyl)piperazine; 3,5-Difluorophenylpiperazine; Piperazine, 1-(3,5-difluorophenyl)-; 180698-14-0; 3,5-Difluoro-1-piperazinylbenzene; 1-(3,5-Difluorophenyl)piperazine hydrochloride (salt form); DFPP
EINECS	Contact for details

Quality Control

Our 1-(3,5-Difluorophenyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.