Description

4,6-Dibromo-2-[4-(Trifluoromethyl)Phenyl]Pyrimidine is a high-value, multi-functional halogenated pyrimidine building block designed for advanced chemical synthesis. Its molecular structure, featuring bromine atoms and a trifluoromethylphenyl group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the pyrimidine core.
• Material Science Research: Serves as a building block for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport molecules.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis and organocatalysts due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and R&D: A versatile starting material for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	4,6-Dibromo-2-[4-(Trifluoromethyl)Phenyl]Pyrimidine
CAS No.	180608-06-4
Molecular Formula	C11H5Br2F3N2
Molecular Weight	405.97 g/mol
Synonyms	2-(4-Trifluoromethylphenyl)-4,6-dibromopyrimidine; 4,6-Dibromo-2-(4-trifluoromethylphenyl)pyrimidine; 4,6-Dibromo-2-(α,α,α-trifluoro-p-tolyl)pyrimidine; 4,6-Dibromo-2-(4-(trifluoromethyl)phenyl)pyrimidine; 2-(4-(Trifluoromethyl)phenyl)-4,6-dibromopyrimidine; 4,6-Dibromo-2-p-trifluoromethylphenylpyrimidine
EINECS	Contact for details

Quality Control

Every batch of 4,6-Dibromo-2-[4-(Trifluoromethyl)Phenyl]Pyrimidine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids/bases and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.