Description

4-Chloro-6-Methyl-2-(3-Methylphenyl)Pyrimidine is a high-purity pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its specific substitution pattern makes it a valuable intermediate for constructing complex molecules with targeted biological or material properties. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its pyrimidine core.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	4-Chloro-6-Methyl-2-(3-Methylphenyl)Pyrimidine
CAS No.	180606-70-6
Molecular Formula	C12H11ClN2
Molecular Weight	218.68 g/mol
Synonyms	2-(3-Methylphenyl)-4-chloro-6-methylpyrimidine; 4-Chloro-2-(m-tolyl)-6-methylpyrimidine; 4-Chloro-6-methyl-2-(3-methylphenyl)pyrimidine; 4-Chloro-6-methyl-2-m-tolylpyrimidine; 2-(3-Methylphenyl)-4-chloro-6-methyl-pyrimidine; 180606-70-6; 4-Chloro-2-(3-methylphenyl)-6-methylpyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Methyl-2-(3-Methylphenyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.