Description

(R)-1-(6-Chloro-9H-Purin-9-Yl)Propan-2-Ol is a high-purity chiral purine derivative, a key synthetic intermediate in modern pharmaceutical research and development. Its value lies in its role as a critical building block for the synthesis of nucleoside analogs and other bioactive molecules, enabling the creation of targeted therapeutics. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of novel antiviral and anticancer nucleoside analog drugs.
• Biochemical Research: Used in the study of enzyme-substrate interactions, particularly those involving purine-based enzymes and receptors.
• Process Chemistry: Serves as a key starting material or intermediate in the scalable production of active pharmaceutical ingredients (APIs).
• Proteomics & Molecular Biology: Can be utilized in the development of labeled probes or inhibitors for studying cellular processes.
• Custom Synthesis: A foundational compound for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	(R)-1-(6-Chloro-9H-Purin-9-Yl)Propan-2-Ol
CAS No.	180587-74-0
Molecular Formula	C8H9ClN4O
Molecular Weight	212.63 g/mol
Synonyms	(R)-1-(6-Chloropurin-9-yl)propan-2-ol; (R)-6-Chloro-9-(2-hydroxypropyl)purine; (R)-9-(2-Hydroxypropyl)-6-chloropurine; (R)-6-Chloro-9-(1-methyl-2-hydroxyethyl)purine; (R)-Isopropyl 6-chloropurine alcohol; (R)-1-(6-Chloro-9H-purin-9-yl)-2-propanol; (R)-6-Chloropurine isopropanol derivative
EINECS	Contact for details

Quality Control

Our (R)-1-(6-Chloro-9H-Purin-9-Yl)Propan-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and development use. Certificates of Analysis (COA) documenting identity, purity, and chiral excess are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.