Description

Amyloid P Component (33-38) Amide is a synthetic peptide fragment corresponding to a specific region of the human serum amyloid P component (SAP), a key protein involved in amyloid fibril formation and innate immunity. This compound is of significant value as a critical research tool for studying protein aggregation mechanisms, amyloidosis diseases, and the structural biology of pentraxins. It serves researchers and developers in pharmaceutical R&D, academic biochemistry, and diagnostic kit manufacturing who require high-purity, well-characterized peptides for assay development, antibody production, and inhibitor screening.

Application

• Biomedical Research: Used as a reference standard or antigen in studies of amyloidosis, Alzheimer's disease, and other protein misfolding disorders.
• Antibody Development: Serves as an immunogen for generating specific polyclonal or monoclonal antibodies against the SAP protein.
• Diagnostic Assays: Employed in the development and calibration of ELISA, Western blot, or other immunoassays to detect SAP or related biomarkers.
• Mechanistic Studies: Facilitates in vitro binding studies to investigate interactions between SAP and other ligands like glycosaminoglycans or DNA.
• Drug Discovery: Acts as a target peptide in high-throughput screening campaigns to identify potential inhibitors of SAP-mediated amyloid deposition.
• Quality Control: Used as a system suitability standard in analytical methods for related pharmaceutical peptides or biologics.

Basic Information

Product Name	Amyloid P Component (33-38) Amide
CAS No.	180387-76-2
Molecular Formula	C31H53N11O9
Molecular Weight	723.83 g/mol
Synonyms	Serum Amyloid P Component (33-38) amide; SAP (33-38) amide; H-Arg-Gly-Val-Phe-Glu-Val-NH2; Amyloid P Component Peptide (33-38); Arg-Gly-Val-Phe-Glu-Val-amide; Pentapeptide Amyloid P (33-38); AP Component (33-38) Amide
EINECS	Contact for details

Quality Control

Every batch of Amyloid P Component (33-38) Amide is produced and analyzed under stringent conditions to ensure identity, purity, and consistency. Our quality system employs advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and analytical data is provided with each shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive). For long-term stability, store desiccated at -20°C. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 8.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.