Description

2-[({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Methyl]Butanoic Acid is a specialized Fmoc-protected amino acid derivative, a critical building block in modern solid-phase peptide synthesis (SPPS). Its primary value lies in enabling the controlled and efficient construction of complex peptides by protecting the amino group during chain elongation. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid building block for the automated synthesis of custom peptides.
• Pharmaceutical Research & Development: Used in the discovery and production of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or carriers.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify bioactive compounds.
• Proteomics & Biochemical Studies: Utilized in the synthesis of peptide fragments for antibody production, enzyme substrates, or inhibitors.
• Material Science: Can be incorporated into peptide-based polymers or biomaterials for specialized applications.

Basic Information

Product Name	2-[({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Methyl]Butanoic Acid
CAS No.	180181-95-7
Molecular Formula	C20H21NO4
Molecular Weight	339.39 g/mol
Synonyms	Fmoc-2-Aminomethylbutyric Acid; Fmoc-Amb-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-(aminomethyl)butanoic Acid; 2-({[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}methyl)butanoic Acid; Fmoc-2-(Aminomethyl)butyric Acid; N-Fmoc-2-(aminomethyl)butanoic Acid; (2S)-2-({[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}methyl)butanoic Acid (for enantiopure form)
EINECS	Contact for details

Quality Control

Our 2-[({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Methyl]Butanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis (where applicable), and identity confirmation, to ensure it meets the stringent requirements of peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require desiccant. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation (if chiral)	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.