Description

2-Methoxy-4,6-Bis(trifluoromethyl)benzaldehyde is a specialized fluorinated aromatic aldehyde building block. This compound matters for its unique trifluoromethyl groups, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of advanced molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for developing active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to improve chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, condensations, and as a directing group in complex multi-step synthetic routes.
• Fluorinated Dye & Pigment Precursor: Enables the synthesis of novel fluorinated colorants with enhanced performance characteristics.

Basic Information

Product Name	2-Methoxy-4,6-Bis(trifluoromethyl)benzaldehyde
CAS No.	180134-14-9
Molecular Formula	C11H6F6O2
Molecular Weight	284.16 g/mol
Synonyms	4,6-Bis(trifluoromethyl)-2-methoxybenzaldehyde; 2-Methoxy-α,α,α,α',α',α'-hexafluoromesitaldehyde; 2-Methoxy-4,6-bis(trifluoromethyl)benzenecarboxaldehyde; 4,6-Bis(trifluoromethyl)-o-anisaldehyde; 2-Methoxy-4,6-di(trifluoromethyl)benzaldehyde; 2-Methoxy-4,6-bis(trifluoromethyl)benzaldehyde; 180134-14-9; 2-Methoxy-4,6-bis(trifluoromethyl)benzene-1-carbaldehyde
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4,6-Bis(trifluoromethyl)benzaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.