Description

2,2,2-Trifluoro-1-(4-Methoxy-Phenyl)-Ethylamine is a high-value fluorinated aromatic amine building block. This compound is critical for introducing the trifluoroethylamine pharmacophore into advanced molecular structures, significantly altering their physicochemical and biological properties. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral precursor for the development of active pharmaceutical ingredients (APIs), particularly in CNS and metabolic disease research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Ligand & Catalyst Development: Serves as a building block for sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Incorporated into specialty polymers and advanced organic electronic materials to modify solubility and electronic characteristics.
• Fluorine Chemistry Research: An essential reagent for studying structure-activity relationships (SAR) in medicinal and synthetic chemistry programs.

Basic Information

Product Name	2,2,2-Trifluoro-1-(4-Methoxy-Phenyl)-Ethylamine
CAS No.	179996-42-0
Molecular Formula	C9H10F3NO
Molecular Weight	205.18 g/mol
Synonyms	1-(4-Methoxyphenyl)-2,2,2-trifluoroethanamine; α-(Trifluoromethyl)-4-methoxybenzylamine; 4-Methoxy-α-(trifluoromethyl)benzylamine; (4-Methoxyphenyl)(trifluoromethyl)methylamine; 2,2,2-Trifluoro-1-(4-methoxyphenyl)ethanamine; 1-(4-Methoxyphenyl)-2,2,2-trifluoroethylamine; p-Methoxy-α-(trifluoromethyl)benzylamine
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(4-Methoxy-Phenyl)-Ethylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Enantiomer specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.