Description

Benzeneethanol, β-Amino-2-Fluoro- (9Ci) is a specialized fluorinated aromatic amine building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines a fluorinated benzene ring with an ethanolamine side chain, enabling precise structural modifications in target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: An essential building block for academic and industrial research exploring structure-activity relationships (SAR) in fluorinated compounds.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fluorinated aromatics for electronic materials and specialty polymers.
• Bioconjugation Linker: Potential use in developing probes and conjugates for biochemical and diagnostic applications due to its amine and hydroxyl functional groups.

Basic Information

Product Name	Benzeneethanol, β-Amino-2-Fluoro- (9Ci)
CAS No.	179811-62-2
Molecular Formula	C8H10FNO
Molecular Weight	155.17 g/mol
Synonyms	2-(2-Aminoethyl)-6-fluorophenol; 6-Fluoro-2-hydroxybenzeneethanamine; 2-(2-Fluorophenyl)ethanolamine; β-Amino-2-fluorobenzeneethanol; 2-(2-Fluoro-6-hydroxyphenyl)ethan-1-amine; 2-Fluoro-β-hydroxy-phenethylamine; 1-(2-Fluorophenyl)-2-aminoethanol (tautomeric form); FPEA
EINECS	Contact for details

Quality Control

Our Benzeneethanol, β-Amino-2-Fluoro- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0% (by titration)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.