Description

4-Chloro-2-Piperazin-1-Yl-Pyrimidine is a high-value pharmaceutical intermediate and versatile heterocyclic building block. This compound matters for its critical role in the synthesis of complex molecules, particularly in medicinal chemistry for drug discovery and development. Pharmaceutical R&D teams, agrochemical manufacturers, and specialty chemical producers need this precise chemical scaffold to create novel active ingredients targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a building block for creating novel pesticides and herbicides with specific modes of action.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Chloro-2-Piperazin-1-Yl-Pyrimidine
CAS No.	179756-90-2
Molecular Formula	C8H12ClN5
Molecular Weight	213.67 g/mol
Synonyms	4-Chloro-2-(1-piperazinyl)pyrimidine; 2-(Piperazin-1-yl)-4-chloropyrimidine; 4-Chloro-2-piperazin-1-ylpyrimidine; 4-Chloro-2-(piperazin-1-yl)pyrimidine; 179756-90-2; 4-Chloro-2-piperazinylpyrimidine; 2-(1-Piperazinyl)-4-chloropyrimidine; 4-Chloro-2-(1-piperazinyl)-pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Piperazin-1-Yl-Pyrimidine is produced under strict quality management systems. We offer material suitable for research and development use, with specifications tailored to project requirements. All batches undergo rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), physical characteristics, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.