Description

6-Hydroxy-7-Methoxy-3,4-Dihydroquinazolin-4-One is a high-purity, synthetically derived quinazolinone derivative that serves as a critical advanced pharmaceutical intermediate and a versatile scaffold for medicinal chemistry research. Its unique fused heterocyclic structure makes it a valuable building block for the development of novel bioactive compounds targeting a range of therapeutic areas. This compound is primarily sought by research institutions and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those with quinazoline-based pharmacophores.
• Medicinal Chemistry Research: Used as a core scaffold for designing and synthesizing new chemical entities (NCEs) for biological screening.
• Kinase Inhibitor Development: Serves as a starting material for compounds targeting various kinase enzymes, which are implicated in cancer and inflammatory diseases.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes to create more complex heterocyclic systems for material science or agrochemical research.

Basic Information

Product Name	6-Hydroxy-7-Methoxy-3,4-Dihydroquinazolin-4-One
CAS No.	179688-52-9
Molecular Formula	C9H8N2O3
Molecular Weight	192.17 g/mol
Synonyms	6-Hydroxy-7-methoxy-3,4-dihydro-4-quinazolinone; 7-Methoxy-6-hydroxy-3,4-dihydroquinazolin-4-one; 4(3H)-Quinazolinone, 6-hydroxy-7-methoxy-3,4-dihydro-; 179688-52-9; 6-Hydroxy-7-methoxy-1,2,3,4-tetrahydroquinazolin-4-one
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-7-Methoxy-3,4-Dihydroquinazolin-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.