Description

7-Acetoxy-4-Chloro-6-Methoxyquinazoline is a high-purity, synthetically valuable quinazoline derivative. This compound serves as a critical advanced intermediate in the development of novel pharmaceutical agents, particularly in kinase inhibitor research. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to build complex heterocyclic structures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of targeted kinase inhibitors for oncology and other therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides and fungicides based on quinazoline chemistry.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization to create libraries of novel compounds for screening.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs in universities and contract research organizations (CROs).
• API Development: Employed in the route scouting and process development for potential Active Pharmaceutical Ingredients (APIs).

Basic Information

Item	Details
Product Name	7-Acetoxy-4-Chloro-6-Methoxyquinazoline
CAS No.	179688-03-0
Molecular Formula	C11H9ClN2O3
Molecular Weight	252.65 g/mol
Synonyms	4-Chloro-6-methoxy-7-quinazolinyl acetate; 7-Acetoxy-4-chloro-6-methoxyquinazoline; 4-Chloro-6-methoxy-7-acetoxyquinazoline; 7-(Acetyloxy)-4-chloro-6-methoxyquinazoline; 179688-03-0; 4-Chloro-7-acetoxy-6-methoxyquinazoline; 6-Methoxy-4-chloro-7-quinazolinol acetate
EINECS	Contact for details

Quality Control

Our 7-Acetoxy-4-Chloro-6-Methoxyquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.