Description

6-Methoxy-7-Benzyloxyquinazolin-4-One is a high-purity, advanced pharmaceutical intermediate belonging to the quinazolinone class of heterocyclic compounds. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its precise molecular structure that enables targeted drug development. It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of tyrosine kinase inhibitors and other targeted cancer therapies.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• API Synthesis: Serves as a core scaffold in the production of complex, high-value active pharmaceutical ingredients.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Utilized in biochemical assays to study enzyme inhibition and cellular signaling pathways.

Basic Information

Item	Details
Product Name	6-Methoxy-7-Benzyloxyquinazolin-4-One
CAS No.	179688-01-8
Molecular Formula	C₁₆H₁₄N₂O₃
Molecular Weight	282.30 g/mol
Synonyms	6-Methoxy-7-(benzyloxy)quinazolin-4(3H)-one; 7-(Benzyloxy)-6-methoxy-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 7-(benzyloxy)-6-methoxy-; 6-Methoxy-7-benzyloxy-4-quinazolinone; 179688-01-8; Quinazolin-4-one, 6-methoxy-7-benzyloxy-
EINECS	Contact for details

Quality Control

Our 6-Methoxy-7-Benzyloxyquinazolin-4-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.