Description

1-(3-Fluorophenyl)Cyclobutanamine is a fluorinated cyclobutylamine derivative, a versatile organic building block prized for its unique structural motif that combines a rigid cyclobutane ring with a substituted aromatic system. This compound is of significant value in advanced organic synthesis, particularly for constructing complex molecular architectures with tailored physicochemical properties. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the design and synthesis of new generation herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, or organic electronic materials due to its fluorinated aromatic group.
• Chemical Biology Probe: Utilized as a scaffold for creating molecular probes to study enzyme function or protein-protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring fluorinated cyclobutane chemistry.

Basic Information

Product Name	1-(3-Fluorophenyl)Cyclobutanamine
CAS No.	179411-86-0
Molecular Formula	C10H12FN
Molecular Weight	165.21 g/mol
Synonyms	1-(3-Fluorophenyl)cyclobutanamine; 3-Fluoro-α-cyclobutylbenzenemethanamine; 1-(3-Fluorophenyl)cyclobutan-1-amine; 3-Fluorophenylcyclobutylamine; N-(3-Fluorophenyl)cyclobutanamine; 1-Amino-1-(3-fluorophenyl)cyclobutane; (3-Fluorophenyl)cyclobutylamine
EINECS	Contact for details

Quality Control

Our 1-(3-Fluorophenyl)Cyclobutanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and cGMP-grade synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.