Description

5-Fluoro-3-(Trifluoromethyl)Benzene-1,2-Diamine is a high-value, multi-fluorinated aromatic diamine building block. This compound is critical for synthesizing advanced materials and active pharmaceutical ingredients (APIs) due to the unique electronic and steric properties imparted by its fluorine substituents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced biological activity and material performance.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used to build advanced herbicide and pesticide molecules where fluorine atoms improve metabolic stability and membrane permeability.
• Functional Material Building Block: Serves as a monomer or cross-linker in the production of high-performance polymers, such as polyimides and polyamides, for electronics and aerospace applications.
• Ligand and Catalyst Development: Employed in the design of novel chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments for advanced imaging and display technologies.
• Research & Development: A versatile reagent for academic and industrial research exploring structure-activity relationships (SAR) in medicinal chemistry.

Basic Information

Product Name	5-Fluoro-3-(Trifluoromethyl)Benzene-1,2-Diamine
CAS No.	179062-02-3
Molecular Formula	C7H6F4N2
Molecular Weight	194.13 g/mol
Synonyms	1,2-Diamino-5-fluoro-3-(trifluoromethyl)benzene; 3-Trifluoromethyl-5-fluoro-1,2-phenylenediamine; 5-Fluoro-3-(trifluoromethyl)-1,2-benzenediamine; 5-Fluoro-3-(trifluoromethyl)-o-phenylenediamine; 2-Amino-4-fluoro-6-(trifluoromethyl)aniline; 4-Fluoro-2-(trifluoromethyl)-1,3-benzenediamine; 179062-02-3; 5-Fluoro-3-trifluoromethylbenzene-1,2-diamine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-(Trifluoromethyl)Benzene-1,2-Diamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply chain integrity and traceability ensures you receive a reliable material for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.