Description

Acetyl-Amylin (8-37) (Mouse, Rat) is a specific, acetylated fragment of the amylin peptide, a key hormone involved in glucose metabolism. This high-purity research compound is critical for studying the physiological and pathological roles of amylin in rodent models, particularly in diabetes and obesity research. It is an essential tool for pharmaceutical R&D, academic institutions, and contract research organizations (CROs) focused on metabolic disorders and endocrine signaling pathways.

Application

• Pharmacological Research: Used as a selective amylin receptor antagonist to investigate the physiological effects of amylin in mouse and rat models.
• Diabetes & Metabolic Studies: Critical for elucidating the role of amylin in glucose homeostasis, insulin secretion, and satiety signaling.
• Receptor Binding Assays: Employed in competitive binding studies to characterize amylin receptor subtypes and affinity.
• In Vivo Animal Studies: Administered in rodent studies to block endogenous amylin action, helping to define its contribution to disease states.
• Biochemical Pathway Analysis: A key reagent for dissecting intracellular signaling cascades activated by amylin.
• Drug Discovery & Development: Serves as a reference standard and tool compound in screening for novel amylin-based therapeutics.

Basic Information

Product Name	Acetyl-Amylin (8-37) (Mouse, Rat)
CAS No.	178603-82-2
Molecular Formula	C149H246N44O47S2
Molecular Weight	3379.0 g/mol
Synonyms	Acetyl-Amylin (8-37), Mouse/Rat; Acetylated Amylin Fragment 8-37; Amylin (8-37), N-acetyl-; Amylin Receptor Antagonist (8-37); rAmy (8-37); [Ac]Amylin(8-37); IAPP (8-37) (mouse, rat), acetyl-; N-Acetyl-Islet Amyloid Polypeptide (8-37)
EINECS	Contact for details

Quality Control

Every batch of Acetyl-Amylin (8-37) (Mouse, Rat) is manufactured under strict quality systems and undergoes comprehensive analytical characterization. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for purity, identity, and peptide content.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.