Description

Z-Phe-Asp-Oh is a protected dipeptide building block, specifically the benzyloxycarbonyl (Z) derivative of phenylalanyl-aspartic acid. This compound is a critical intermediate in the synthesis of complex peptides and peptidomimetics, offering precise control over stereochemistry and sequence. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, proteomics research, and the development of enzyme inhibitors.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected fragment for the automated or manual assembly of longer peptide chains.
• Pharmaceutical Intermediate: Used in the research and development of therapeutic peptides targeting various diseases.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies, particularly those involving aspartic proteases.
• Peptidomimetic Design: A starting material for creating non-peptide compounds that mimic peptide structure and function.
• Custom Peptide Services: A fundamental building block supplied to CROs and CDMOs for client-specific peptide production.

Basic Information

Product Name	Z-Phe-Asp-Oh
CAS No.	178403-40-2
Molecular Formula	C₂₁H₂₂N₂O₇
Molecular Weight	414.41 g/mol
Synonyms	N-Benzyloxycarbonyl-L-phenylalanyl-L-aspartic acid; Z-L-Phe-L-Asp-OH; Z-Phenylalanyl-Aspartic Acid; N-Cbz-L-phenylalanyl-L-aspartic acid; Cbz-Phe-Asp-OH; (2S)-2-[[(2S)-2-(benzyloxycarbonylamino)-3-phenylpropanoyl]amino]butanedioic acid; Z-F-D; ZFD-OH
EINECS	Contact for details

Quality Control

Our Z-Phe-Asp-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	-10.0° to -15.0° (c=1, DMF)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.