Description

4,6-Dimethoxy-n-[3-(Trifluoromethyl)-2-Pyridinyl]-2-Pyrimidinamine is a high-purity chemical intermediate of significant importance in advanced organic synthesis. This compound is valued for its unique pyrimidine-pyridine hybrid structure, which serves as a critical building block in the development of novel active ingredients. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for creating new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Research: Serves as a core scaffold for developing new-generation herbicides and fungicides, leveraging the trifluoromethyl pyridine moiety for enhanced bioactivity and environmental profile.
• Chemical Synthesis Building Block: Used in organic chemistry research for constructing complex heterocyclic compounds due to its reactive amine and dimethoxy pyrimidine groups.
• Material Science: Potential application in the development of specialty chemicals and functional materials, such as ligands for catalysis or components in electronic materials.

Basic Information

Product Name	4,6-Dimethoxy-n-[3-(Trifluoromethyl)-2-Pyridinyl]-2-Pyrimidinamine
CAS No.	178403-36-6
Molecular Formula	C₁₂H₁₁F₃N₄O₂
Molecular Weight	300.24 g/mol
Synonyms	4,6-Dimethoxy-N-[3-(trifluoromethyl)pyridin-2-yl]pyrimidin-2-amine; 2-Pyrimidinamine, 4,6-dimethoxy-N-[3-(trifluoromethyl)-2-pyridinyl]-; N-(3-(Trifluoromethyl)pyridin-2-yl)-4,6-dimethoxypyrimidin-2-amine; 4,6-Dimethoxy-2-((3-(trifluoromethyl)pyridin-2-yl)amino)pyrimidine; CAS 178403-36-6
EINECS	Contact for details

Quality Control

Our 4,6-Dimethoxy-n-[3-(trifluoromethyl)-2-pyridinyl]-2-pyrimidinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.