Description

n-Me-D-Tyr-Oh CAS NO 178357-84-1 is a high-purity, non-natural amino acid derivative, specifically the N-methylated form of D-Tyrosine. This compound is a critical chiral building block in advanced pharmaceutical research and development, offering unique steric and electronic properties for modulating peptide bioactivity and stability. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel peptide-based therapeutics, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex peptide drugs and active pharmaceutical ingredients (APIs).
• Peptidomimetic Research: Used to introduce N-methylation into peptide backbones to enhance metabolic stability, membrane permeability, and receptor selectivity.
• Protease Inhibitor Development: Serves as a core structural component in the design of selective enzyme inhibitors.
• Biochemical Tool Compound: Employed in academic and industrial research to study enzyme-substrate interactions and signal transduction pathways.
• Labeled Compound Synthesis: A precursor for the preparation of isotopically labeled (e.g., 13C, 15N) peptides for metabolic and pharmacokinetic studies.
• Combinatorial Chemistry Libraries: A valuable building block for generating diverse compound libraries for high-throughput screening.

Basic Information

Product Name	n-Me-D-Tyr-Oh
CAS No.	178357-84-1
Molecular Formula	C10H13NO3
Molecular Weight	195.22 g/mol
Synonyms	N-Methyl-D-tyrosine; (R)-2-Amino-3-(4-hydroxyphenyl)-N-methylpropanoic acid; D-N-Methyltyrosine; D-α-Methyltyrosine; D-MT; H-D-Tyr(Me)-OH; (R)-N-Methyltyrosine; D-Tyrosine, N-methyl-
EINECS	Contact for details

Quality Control

Our n-Me-D-Tyr-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile is supplied with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% de (D-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.