Description

2-Pyrimidinamine, 4-(3,4-Dihydro-1-Methyl-2(1H)-Isoquinolinyl)-n-(4-Fluorophenyl)-5,6-Dimethyl-, Monohydrochloride is a high-purity, non-peptidic small molecule compound designed for advanced research and development. This product is critical for pharmaceutical and agrochemical innovators seeking to explore novel therapeutic and bioactive pathways. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for hit-to-lead optimization and as a key synthetic intermediate.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates targeting specific biological pathways.
• Biochemical Research: Used as a reference standard or active probe in enzymatic and receptor-binding assays to study structure-activity relationships (SAR).
• Agrochemical Development: Acts as a key intermediate in the research and synthesis of new-generation crop protection agents and pesticides.
• Chemical Biology: Employed in the development of chemical tools and molecular probes for cellular and in vitro studies.
• Process Chemistry: Utilized in route scouting and scale-up studies for the efficient production of complex active pharmaceutical ingredients (APIs).
• Academic Research: Supports fundamental chemical and pharmacological research in university and institutional laboratories.

Basic Information

Product Name	2-Pyrimidinamine, 4-(3,4-Dihydro-1-Methyl-2(1H)-Isoquinolinyl)-n-(4-Fluorophenyl)-5,6-Dimethyl-, Monohydrochloride
CAS No.	178307-42-1
Molecular Formula	C22H23FN4·HCl
Molecular Weight	398.91 g/mol
Synonyms	4-(1-Methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine hydrochloride; 4-(1-Methyl-3,4-dihydro-1H-isoquinolin-2-yl)-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine monohydrochloride; 2-Pyrimidinamine, 4-(1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)-N-(4-fluorophenyl)-5,6-dimethyl-, hydrochloride (1:1); 178307-42-1; 4-(1-Methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-N-(4-fluorophenyl)-5,6-dimethyl-2-pyrimidinamine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Pyrimidinamine, 4-(3,4-Dihydro-1-Methyl-2(1H)-Isoquinolinyl)-n-(4-Fluorophenyl)-5,6-Dimethyl-, Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.