Description

5-Hydroxy-2-Iodotyrosine is a halogenated derivative of the amino acid tyrosine, characterized by the presence of iodine and a hydroxyl group on its aromatic ring. This specific structural modification makes it a valuable advanced pharmaceutical intermediate and a crucial building block in organic synthesis. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing novel bioactive compounds and radiopharmaceutical precursors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of thyroid hormone analogs and other iodinated bioactive molecules.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving tyrosine metabolism or halogenation pathways.
• Radiopharmaceutical Development: Serves as a starting material for labeling with radioactive iodine isotopes (e.g., I-123, I-125, I-131) for diagnostic imaging or therapeutic agents.
• Organic Synthesis Building Block: Employed in the construction of complex molecules for medicinal chemistry and material science applications.
• Reference Standard: Used in analytical laboratories for method development, calibration, and quality control of related compounds.

Basic Information

Item	Detail
Product Name	5-Hydroxy-2-Iodotyrosine
CAS No.	178273-55-7
Molecular Formula	C9H10INO4
Molecular Weight	323.09 g/mol
Synonyms	2-Iodo-5-hydroxyphenylalanine; 3-(2-Iodo-5-hydroxyphenyl)alanine; 5-Hydroxy-2-iodo-DL-tyrosine; 2-Iodo-5-hydroxytyrosine; (RS)-2-Amino-3-(2-iodo-5-hydroxyphenyl)propanoic acid; Iodotyrosine derivative; 5-OH-2-I-Tyr
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-2-Iodotyrosine is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all test results against predefined specifications. Our quality commitment ensures consistency and reliability for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.