Description

n-(3-Chloro-4-Fluorophenyl)-6-(Methylthio)Pyrimido[5,4-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery. It is primarily utilized by research institutions and pharmaceutical manufacturers developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) for drug discovery and development programs.
• Kinase Inhibitor Research: Serves as a core scaffold or intermediate in the design and synthesis of potential kinase inhibitors for oncology and other therapeutic areas.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization to develop new chemical entities with targeted biological activity.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme function and cellular signaling pathways.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	n-(3-Chloro-4-Fluorophenyl)-6-(Methylthio)Pyrimido[5,4-D]Pyrimidin-4-Amine
CAS No.	177908-24-6
Molecular Formula	C13H9ClFN5S
Molecular Weight	333.76 g/mol
Synonyms	6-(Methylthio)-N-(3-chloro-4-fluorophenyl)pyrimido[5,4-d]pyrimidin-4-amine; 6-Methylsulfanyl-N-(3-chloro-4-fluoro-phenyl)pyrimido[5,4-d]pyrimidin-4-amine; 177908-24-6; Pyrimido[5,4-d]pyrimidin-4-amine, 6-(methylthio)-N-(3-chloro-4-fluorophenyl)-; N-(3-Chloro-4-fluorophenyl)-6-(methylthio)pyrimido[5,4-d]pyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our n-(3-Chloro-4-Fluorophenyl)-6-(Methylthio)Pyrimido[5,4-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.