Description

Ethyl [(3-Amino-4-Oxo-3,4-Dihydroquinazolin-2-Yl)Thio]Acetate is a specialized heterocyclic building block featuring a quinazolinone core with a thioacetate side chain. This compound matters as a key synthetic intermediate for the development of novel pharmaceutical agents, particularly in medicinal chemistry research targeting specific enzyme inhibition. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapeutics.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Serves as a building block for developing new active ingredients for crop protection products.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Biochemical Tool Compound: Can be utilized to develop probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	Ethyl [(3-Amino-4-Oxo-3,4-Dihydroquinazolin-2-Yl)Thio]Acetate
CAS No.	177592-08-4
Molecular Formula	C₁₂H₁₃N₃O₃S
Molecular Weight	279.32 g/mol
Synonyms	2-[(3-Amino-4-oxo-3,4-dihydroquinazolin-2-yl)thio]acetic acid ethyl ester; Ethyl 2-[(3-amino-4-oxo-3H-quinazolin-2-yl)thio]acetate; 2-[(3-Amino-4-oxo-3,4-dihydro-2-quinazolinyl)thio]acetic Acid Ethyl Ester; Ethyl (3-amino-4-oxo-3,4-dihydroquinazolin-2-yl)sulfanylacetate; Quinazolinone thioacetate derivative; CAS 177592-08-4
EINECS	Contact for details

Quality Control

Our Ethyl [(3-Amino-4-Oxo-3,4-Dihydroquinazolin-2-Yl)Thio]Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.