Description

Galanin (1-13)-Mastoparan is a synthetic peptide chimera that combines the N-terminal fragment of the neuropeptide galanin with the potent wasp venom peptide mastoparan. This engineered compound is valued for its unique ability to modulate G-protein signaling and its cell-penetrating properties, making it a powerful tool for biomedical research. It is primarily utilized by researchers in neurobiology, pharmacology, and cell biology to study receptor interactions, intracellular signaling pathways, and peptide-based drug delivery mechanisms.

Application

• Neuroscience Research: Investigation of galanin receptor (GalR) subtypes and their downstream signaling cascades in the central and peripheral nervous systems.
• Signal Transduction Studies: Used as a research tool to probe G-protein activation and inhibition mechanisms due to its mastoparan-derived activity.
• Cell Permeability & Drug Delivery: Serves as a model cell-penetrating peptide (CPP) for studying the intracellular delivery of cargo molecules.
• Pharmacological Profiling: Screening and characterization of novel compounds targeting neuropeptide pathways.
• Biochemical Assay Development: A key reagent in developing in vitro assays for high-throughput screening of potential therapeutics.
• Academic & Institutional Research: Fundamental research in universities and institutes focusing on peptide chemistry and neuropeptide function.

Basic Information

Product Name	Galanin (1-13)-Mastoparan
CAS No.	177352-81-7
Molecular Formula	C95H150N30O22
Molecular Weight	2152.4 g/mol
Synonyms	Galanin (1-13)-Mastoparan; Galanin-Mastoparan Chimeric Peptide; Galanin(1-13)-Mastoparan; Galanin-Mastoparan Conjugate; GWTLNSAGYLLGP-INLKALAALAKKIL-NH2 (Sequence); Mastoparan-Galanin Chimera; Neuropeptide Research Peptide
EINECS	Contact for details

Quality Control

Our Galanin (1-13)-Mastoparan is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and peptide content. We adhere to ISO 9001 quality management standards, and our production is designed to meet the rigorous requirements of the research community.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	Within ± 10% of theoretical
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.