Description

Acridinium C2 NHS Ester is a high-purity, reactive labeling reagent designed for the covalent conjugation of biomolecules. This compound is critical for researchers and manufacturers requiring stable, luminescent labels for sensitive detection and diagnostic applications. It is primarily utilized in the development of chemiluminescent immunoassays (CLIA), nucleic acid detection probes, and other advanced bioanalytical platforms within the pharmaceutical, biotechnology, and in vitro diagnostics (IVD) industries.

Application

• Chemiluminescent Immunoassay (CLIA) Development: Conjugation to antibodies or antigens to create highly sensitive detection reagents for clinical diagnostics.
• Nucleic Acid Labeling: Modification of oligonucleotides for use as probes in hybridization assays, including PCR and next-generation sequencing applications.
• Protein and Peptide Tagging: Site-specific labeling of proteins for studying protein-protein interactions, cellular localization, and activity assays.
• Lateral Flow Assay (LFA) Manufacturing: Production of conjugated detector antibodies for rapid point-of-care test strips.
• Biosensor Fabrication: Immobilization of biomolecules on sensor surfaces to create interfaces for pathogen or biomarker detection.
• Research Reagent: Used in academic and industrial R&D for developing novel assay formats and detection methodologies.

Basic Information

Product Name	Acridinium C2 NHS Ester
CAS No.	177332-37-5
Molecular Formula	C28H28N3O6PF6
Molecular Weight	639.51 g/mol
Synonyms	10-Methyl-9-(2-(N-succinimidyloxycarbonyl)ethyl)acridinium-2-sulfonamide Hexafluorophosphate; Acridinium-9-(N-succinimidyloxycarbonyl)-2-sulfonamide C2 Ester; N-Hydroxysuccinimide Ester of Acridinium C2; Acridinium NHS Ester; Acridinium Labeling Reagent; CLIA Labeling Reagent; Chemiluminescent Acridinium Ester
EINECS	Contact for details

Quality Control

Our Acridinium C2 NHS Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for diagnostic and research applications. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.