Description

n-[6,9-Dihydro-6-Oxo-9-[[2-(1-Oxopropoxy)-1-[(1-Oxopropoxy)Methyl]Ethoxy]Methyl]-1H-Purin-2-Yl]Propanamide is a high-purity, specialized purine derivative designed for advanced research and pharmaceutical development. This compound is valued for its role as a key synthetic intermediate in the creation of novel therapeutic agents, particularly in the fields of oncology and virology. It is primarily sought by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of nucleoside analog prodrugs and targeted antiviral or anticancer agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new purine-based compounds with enhanced biological activity.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to purine metabolism and signaling pathways.
• Preclinical Development: Employed in the formulation and testing of new chemical entities (NCEs) during early-stage drug development.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in analytical laboratories.

Basic Information

Product Name	n-[6,9-Dihydro-6-Oxo-9-[[2-(1-Oxopropoxy)-1-[(1-Oxopropoxy)Methyl]Ethoxy]Methyl]-1H-Purin-2-Yl]Propanamide
CAS No.	177216-32-9
Molecular Formula	C19H25N5O8
Molecular Weight	451.43 g/mol
Synonyms	9-[[2-(Propionyloxy)-1-[(propionyloxy)methyl]ethoxy]methyl]-2-(propionylamino)-1H-purin-6-one; 2-Propionamido-9-[[2-(propionyloxy)-1-[(propionyloxy)methyl]ethoxy]methyl]-1H-purin-6-one; Propanoic acid, 1-methyl-2-[(2-propionamido-6-oxo-1H-purin-9-yl)methoxy]ethyl ester; Bis(PIV) Prodrug Intermediate; Purine Prodrug Intermediate
EINECS	Contact for details

Quality Control

Our n-[6,9-Dihydro-6-Oxo-9-[[2-(1-Oxopropoxy)-1-[(1-Oxopropoxy)Methyl]Ethoxy]Methyl]-1H-Purin-2-Yl]Propanamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities to meet the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.