Description

4-Chloro-2-Fluoro-5-Methoxy Benzaldehyde is a versatile halogenated benzaldehyde derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a specific halogenated aromatic core.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the chloro and fluoro substituents can enhance biological activity and stability.
• Liquid Crystal & OLED Material Research: Serves as a starting material for synthesizing specialized organic compounds used in electronic displays and optoelectronic devices.
• Dye & Pigment Intermediate: Employed in the production of complex dyes and functional pigments, contributing to color fastness and specific light-absorption properties.
• Cross-Coupling Reactions: The aldehyde and halogen groups make it a suitable substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to build biaryl structures.
• Custom Synthesis & Contract Manufacturing: An essential reagent for fine chemical manufacturers and CROs/CMOs producing custom compounds for client projects.

Basic Information

Product Name	4-Chloro-2-Fluoro-5-Methoxy Benzaldehyde
CAS No.	177034-24-1
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	5-Methoxy-2-fluoro-4-chlorobenzaldehyde; 2-Fluoro-5-methoxy-4-chlorobenzaldehyde; 4-Chloro-2-fluoro-5-methoxybenzaldehyde; Benzaldehyde, 4-chloro-2-fluoro-5-methoxy-; 4-Chloro-2-fluoro-5-methoxy-benzaldehyde; 2-Fluoro-4-chloro-5-methoxybenzaldehyde; 5-Methoxy-4-chloro-2-fluorobenzaldehyde
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluoro-5-Methoxy Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.