Description

Ac-Gly-Arg-Gly-NH2 is a synthetic tetrapeptide derivative featuring an acetylated N-terminus and a C-terminal amide. This molecular structure makes it a valuable building block and research tool in peptide chemistry and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications ranging from drug discovery to biochemical studies.

Application

• Pharmaceutical Intermediates: Serves as a key synthetic precursor or a structural motif in the development of novel therapeutic peptides.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving proteases or kinases.
• Peptide Library Synthesis: Employed in combinatorial chemistry for the generation of diverse peptide libraries for screening purposes.
• Cell Biology Studies: Applied in research to investigate cell signaling pathways, protein-protein interactions, and cellular uptake mechanisms.
• Standards and References: Functions as a high-purity analytical standard for method development and quality control in peptide analysis.

Basic Information

Product Name	Ac-Gly-Arg-Gly-NH2
CAS No.	176520-14-2
Molecular Formula	C15H28N8O5
Molecular Weight	400.43 g/mol
Synonyms	Acetyl-Gly-Arg-Gly-amide; N-Acetylglycyl-L-arginylglycinamide; Ac-G-R-G-NH2; H-Ac-GRG-NH2; Ac-Gly-Arg-Gly-CONH2; Tetrapeptide-3 (cosmetic ingredient listing); Nα-Acetylglycyl-Nω-[(aminoiminomethyl)amino]-L-norvalylglycinamide
EINECS	Contact for details

Quality Control

Our Ac-Gly-Arg-Gly-NH2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.