Description

5-Pyrimidinecarboxylic Acid, 2-(1-Methylethyl)-, Methyl Ester (9Ci) is a specialized pyrimidine derivative, a key heterocyclic building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, antiviral agents, and enzyme inhibitors.
• Agrochemical Research: Used in the development and production of advanced pesticides, herbicides, and fungicides where the pyrimidine core provides specific biological activity.
• Material Science: Serves as a precursor for the synthesis of specialty polymers, liquid crystals, and organic electronic materials requiring tailored heterocyclic components.
• Chemical Synthesis: Acts as a versatile synthon in organic chemistry for constructing more complex pyrimidine-based structures through various coupling and functionalization reactions.
• Biochemical Research: Employed in the study of nucleotide analogs and other biologically relevant pyrimidine derivatives for probing metabolic pathways.

Basic Information

Product Name	5-Pyrimidinecarboxylic Acid, 2-(1-Methylethyl)-, Methyl Ester (9Ci)
CAS No.	176240-74-7
Molecular Formula	C9H12N2O2
Molecular Weight	180.20 g/mol
Synonyms	2-Isopropyl-5-pyrimidinecarboxylic acid methyl ester; Methyl 2-isopropylpyrimidine-5-carboxylate; 2-Isopropylpyrimidine-5-carboxylic acid methyl ester; 5-Methoxycarbonyl-2-isopropylpyrimidine; 2-(1-Methylethyl)-5-pyrimidinecarboxylic acid methyl ester; 5-Pyrimidinecarboxylic acid, 2-(1-methylethyl)-, methyl ester; Methyl 2-(propan-2-yl)pyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to cGMP principles where applicable to support our clients in regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.