Description

Pyrimidine, 2-(Methylthio)-5-(Trifluoromethyl)- is a high-value, fluorinated pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique trifluoromethyl and methylthio functional groups, which are instrumental in modulating the physicochemical and biological properties of target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in the development of crop protection agents and potential pharmaceutical intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Serves as a core building block for the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Material Science Research: Used in the synthesis of specialized organic materials and ligands for catalysis, where electronic properties are fine-tuned by the sulfur and fluorine atoms.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	Pyrimidine, 2-(Methylthio)-5-(Trifluoromethyl)-
CAS No.	176214-15-6
Molecular Formula	C6H5F3N2S
Molecular Weight	194.18 g/mol
Synonyms	2-(Methylthio)-5-(trifluoromethyl)pyrimidine; 5-(Trifluoromethyl)-2-methylthiopyrimidine; 2-Methylsulfanyl-5-trifluoromethylpyrimidine; 2-Methylmercapto-5-trifluoromethylpyrimidine; 5-Trifluoromethyl-2-methylthiopyrimidine; 2-(Methylthio)-5-(trifluoromethyl)pyrimidine; 2-Methylthio-5-trifluoromethylpyrimidine
EINECS	Contact for details

Quality Control

Our Pyrimidine, 2-(Methylthio)-5-(Trifluoromethyl)- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications for your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.