Description

Methyl-(5-Trifluoromethyl-Pyrimidin-2-Yl)-Amine is a high-value pyrimidine derivative featuring a trifluoromethyl group, a key structural motif prized in modern chemical synthesis. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for the development of novel active ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to incorporate fluorinated heterocycles into new molecular entities.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the trifluoromethyl-pyrimidine core enhances biological activity and metabolic stability.
• Chemical Research & Development: Serves as a versatile building block for constructing complex heterocyclic libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Material Science Precursor: Potential use in the synthesis of specialty chemicals, ligands for catalysis, and advanced organic electronic materials.

Basic Information

Product Name	Methyl-(5-Trifluoromethyl-Pyrimidin-2-Yl)-Amine
CAS No.	176214-13-4
Molecular Formula	C6H6F3N3
Molecular Weight	177.13 g/mol
Synonyms	2-(Methylamino)-5-(trifluoromethyl)pyrimidine; N-Methyl-5-(trifluoromethyl)pyrimidin-2-amine; 5-(Trifluoromethyl)-2-(methylamino)pyrimidine; Methyl(5-trifluoromethyl-2-pyrimidinyl)amine; 176214-13-4; 2-Pyrimidinamine, N-methyl-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of Methyl-(5-Trifluoromethyl-Pyrimidin-2-Yl)-Amine adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your critical synthesis workflows. Each lot is characterized and tested to confirm identity, purity, and impurity profile. A comprehensive Certificate of Analysis (COA) detailing specifications and test results (e.g., by HPLC, NMR) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.