Description

2-Methyl-5-Trifluoromethyl-Pyrimidine is a high-value fluorinated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a methyl and a trifluoromethyl group on the pyrimidine ring, imparts desirable properties such as enhanced metabolic stability and lipophilicity to target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve bioactivity and environmental persistence.
• Material Science Precursor: Employed in the synthesis of specialty chemicals, ligands for catalysis, and monomers for advanced polymers.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	2-Methyl-5-Trifluoromethyl-Pyrimidine
CAS No.	176214-10-1
Molecular Formula	C6H5F3N2
Molecular Weight	162.11 g/mol
Synonyms	5-(Trifluoromethyl)-2-methylpyrimidine; 2-Methyl-5-(trifluoromethyl)pyrimidine; Pyrimidine, 2-methyl-5-(trifluoromethyl)-; 176214-10-1; 2-Methyl-5-trifluoromethylpyrimidine
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-Trifluoromethyl-Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.