Description

(Rs)-2-(Boc-Amino)-2-(Fmoc-Amino)-Acetic Acid is a sophisticated, dual-protected amino acid derivative designed for advanced synthetic chemistry. This compound is critical for researchers and manufacturers requiring high-purity, chiral building blocks for complex peptide and peptidomimetic synthesis. It is primarily utilized by pharmaceutical R&D teams, biotechnology firms, and fine chemical suppliers engaged in the development of novel therapeutic agents and bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key chiral intermediate for introducing specific amino acid residues with orthogonal protecting groups (Boc and Fmoc).
• Peptidomimetic Drug Discovery: Used in the construction of non-natural peptide backbones to enhance metabolic stability and bioavailability of drug candidates.
• Combinatorial Chemistry Libraries: A valuable building block for creating diverse arrays of compounds for high-throughput screening against biological targets.
• Glycopeptide Synthesis: Facilitates the incorporation of amino acid motifs adjacent to carbohydrate moieties in complex glycopeptide assemblies.
• API (Active Pharmaceutical Ingredient) Development: Employed in the research-scale synthesis of potential peptide-based active ingredients.
• Bioconjugation: Acts as a linker or spacer molecule in the conjugation of peptides to other biomolecules, dyes, or solid supports.

Basic Information

Product Name	(Rs)-2-(Boc-Amino)-2-(Fmoc-Amino)-Acetic Acid
CAS No.	176039-39-7
Molecular Formula	C₂₃H₂₆N₂O₆
Molecular Weight	426.46 g/mol
Synonyms	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[(1,1-dimethylethoxy)carbonyl]glycine; 2-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]acetic Acid; Boc-N-Fmoc-Gly-OH; (RS)-N-Boc-N-Fmoc-glycine; N-Boc-N-Fmoc-glycine, racemic; Nα-Boc-Nα-Fmoc-glycine; 2-(Boc-amino)-2-[(9-fluorenylmethoxycarbonyl)amino]acetic Acid
EINECS	Contact for details

Quality Control

Our (Rs)-2-(Boc-Amino)-2-(Fmoc-Amino)-Acetic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the exacting standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency for your critical synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Racemic mixture
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.